Fertility and Pregnancy Antigens

PAPP-A, heterotetrameric form (htPAPP-A)

Cat.# 8P64

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Cat.#

8P64
Source:

Pooled human retroplacental blood.
Material was tested and found negative for HBsAg, HCV, HIV-1 and 2 antibodies, HCV antibodies, and syphilis.
Composition:

Heterotetrameric complex, consisting of PAPP-A and pro-MBP subunits (PAPP-A/proMBP complex).
Applications:

Calibrator or standard for htPAPP-A or dPAPP-A assays. PAPP-A can be used for in vitro testing of Down syndrome and other fetal disorders.
Analysis:

Purity > 85 % (SDS-PAGE)
Immunological activity:

Immunological activity has been tested with monoclonal antibodies specific to PAPP-A.
Purification:

Ion-exchange chromatography, affinity chromatography, gel-filtration and negative immunoaffinity chromatography.
Presentation:

Lyophilized from solution in 10 mM Tris-HCl, 0.15 M NaCl, pH 7.5.
It is recommended to reconstitute this product with deionized water to its initial concentration.
Storage:

Lyophilized -20°C (-15 … -30 °C allowed)
Reconstituted -70°C (-65 … -80 °C allowed)
Material safety note:

This product is sold for research use only. Standard Laboratory Practices should be followed when handling this material.
References:

See other cardiac markers and blood coagulation products.
See other fertility products.
See all PAPPA-A References.
Search other references from PubMed.
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PAPP-A, heterotetrameric form (htPAPP-A)

Cat.# 8P64

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PAPP-A, heterotetrameric form (htPAPP-A)

Cat.# 8P64

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